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Introduction Verapamil sensitive idiopathic left ventricular
2019-04-19

Introduction Verapamil-sensitive idiopathic left ventricular tachycardia (ILVT) has been shown to be a clinical entity of left-sided idiopathic ventricular tachycardia (VT) [1,2]. In electrophysiological studies, two specific local potentials, the diastolic Purkinje (Pd) potential and presystolic P
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In addition to inducing IKs dysfunction
2019-04-19

In addition to inducing IKs dysfunction through dominant-negative loss-of-function effects and defective channel trafficking, mutations in KCNQ1 suppress IKs channel function by reducing the channel affinity of interacting proteins [68,69]. Phosphatidylinositol-4,5-bisphosphate (PIP2) is a cofactor
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Common and rare SCN A variants may contribute to AF
2019-04-19

Common and rare SCN10A variants may contribute to AF susceptibility [59,60]. SCN10A mutations (R14L and R1268Q) cause a loss of function of Nav1.5 current, which is expected to reduce excitability and lead to the development of the arrhythmogenic substrate responsible for BrS and AF. A common varian
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Aunque m s por afinidad electiva que por propia
2019-04-19

Aunque más por afinidad electiva que por propia decisión del autor, lo cierto es que justamente ese conjunto de rasgos aproximaría la obra al llamado libro de artista, modalidad creativa tan característicamente vanguardista como la simulación crítica, la interdisciplinariedad, el collage, el disposi
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beta amyloid The very fact that providing a greater number o
2019-04-19

The very fact that providing a greater number of doses of IPTp-SP is incrementally effective, even in settings where the parasite is sensitive, also highlights the potential benefit of interventions using more effective drugs. This finding means there is either scope to improve clearance of existing
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En la segunda publicaci n
2019-04-19

En la segunda publicación, “Entrevista con don Carlos Pérez”, éste un ciudadano argentino ficticio recién llegado de Bogotá durante un viaje por Sudamérica, menciona HMBA Linker José María Rivas Groot a propósito de su “Estudio pre liminar”, en el Parnaso colombiano publicado en 1888 y los poetas re
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Podemos seguir con ejemplos espigados el
2019-04-19

Podemos seguir con ejemplos espigados: el plan de instrucción pública del peruano Hipólito Unanue, tras la obligada crítica al antiguo régimen, preveía estudios de “humanidades y filosofía en lengua vulgar entrando después en el estudio del latín los que lo hubieran menester”. En Venezuela se quiso
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El proceso hist rico de conformaci n
2019-04-19

El proceso histórico de conformación del Estado en Chile, su momento constitutivo en el siglo xix es precisamente la invasión del Estado liberal chileno a territorio de los pueblos originarios; desposesión que disocia la comunidad cultural mapuche de la soberanía territorial que hasta ese momento ha
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Por sua vez na Nicar gua
2019-04-18

Por sua vez, na Nicarágua, oleanolic acid Revolução Sandinista de 1979 foi resultado de um acúmulo de forças sociais heterogêneas –camponeses, operários, pobres e marginalizados da cidade e do campo, intelectuais e setores progressistas da burguesia– em torno de um objetivo comum: liquidar o governo
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Fourth social rehabilitation and reintegration of patients w
2019-04-18

Fourth, social rehabilitation and reintegration of patients with fistula along with cytokine inhibitors sensitisation (to prevent the occurrence of fistula, as well as to mitigate against stigmatisation of fistula survivors) will be crucial to eliminate obstetric fistula. Many women might not seek
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The primary outcome was local recurrence
2019-04-18

The primary outcome was local recurrence or metastasis. The secondary outcome included functional outcome based on Musculoskeletal Tumor Society (MSTS) score. Data for the study were retrieved from hospital records, maintained oncological files, surgical files, and clinical examination at the most r
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Although a well experienced group reported a very high succe
2019-04-18

Although a well experienced group reported a very high success rate of 80% after catheter ablation even in patients with congestive heart failure [40], the evidence described above suggests that catheter ablation alone is not sufficient to treat AF in patients with hemodynamic deterioration. This in
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br Other candidate genes br
2019-04-18

Other candidate genes The frequency of minor gene mutations in BrS As mentioned above, more than 10 genes have been reported to cause BrS. The proportions of BrS patients who are mutation carriers, however, are very small, except in the case of SCN5A. In a recent extensive mutation analysis of
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In the present study we firstly confirmed the
2019-04-18

In the present study, we firstly confirmed the resistance of osteosarcoma U2OS clemastine to doxorubicin under hypoxia via inhibiting the drug-induced apoptosis. The hypoxia pre-treatment could significantly ameliorate the viability reduction in U2-os cells which were treated with doxorubicin with
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A partir de las consideraciones que distinguen la institucio
2019-04-18

A partir de las consideraciones que distinguen la institucionalización formal e informal, O’Donnell hace un llamado aminopeptidase inhibitor tener en cuenta las especificidades de las democracias de América Latina y plantea que algunas democracias han subsistido, se han mantenido en el tiempo aun co
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