• br Discussion Prehabilitation is a program to enhance functi

  2019-05-21

  

  Discussion “Prehabilitation” is a program to enhance functional capacity and psychological health to enable patients to withstand an upcoming stressor, e.g. surgery. It is intended to reduce treatment-related morbidity and/or mortality, to decrease length of hospital stay and/or re-admission, and

• br ECM cancer and metastasis For cells

  2019-05-21

  

  ECM, cancer and metastasis For buy candesartan cilexetil to become cancerous they must acquire the ability to survive, grow and invade leading to malignant transformation, tumour formation and ultimately overt secondary metastasis. Abnormal ECM can promote these abilities and is a well-documente

• It is noteworthy that in a recent study

  2019-05-21

  

  It is noteworthy that in a recent study, Le Scouarnec et al. [199]. estimated the burden of rare coding variation in arrhythmia susceptibility genes among 167 BrS index patients and compared that with 167 individuals ≥65 years old with no history of cardiac arrhythmia. The authors concluded that, ex

• Tambi n debemos tener presente

  2019-05-21

  

  También debemos tener presente el horizonte en el que se inscriben colecciones como la aquí revisada. Si aceptamos que nos encontramos bajo un panorama de fragmentación del conocimiento y segmentación de las disciplinas, se muestra fundamental la recuperación de la toma de partida por la cultura, en

• This time last year to coincide with March launched a

  2019-05-21

  

  This time last year, to coincide with (March 9), launched a to highlight the rising burden of kidney disease and to encourage research partnerships to address gaps in knowledge and care, including the affordability of such care. Nephrology research and collaboration has come a relatively long way

• Fourth the enormous investment in accessible medicines and m

  2019-05-20

  

  Fourth, the enormous investment in accessible medicines and medical products without investment in checking their quality is profoundly illogical. WHO estimates that only 7% of sub-Saharan countries had a “moderately functioning MRA”. We cannot expect the world\'s medicine supply to improve without

• La representaci n colectiva de los ind genas se caracteriza

  2019-05-20

  

  La representación colectiva de los indígenas se caracteriza por el tono apologético, idealizado, en el que el uso abundante de los superlativos contribuye Remember resaltar hiperbólicamente la naturaleza pacífica del nativo como “buen salvaje”: Siguiendo el esquema de las oposiciones binarias, Las

• En el segundo grupo se ubican los pueblos ind

  2019-05-20

  

  En el segundo grupo se ubican los pueblos indígenas y comunidades afectadas por la industria extractiva, los mismos que han protagonizado intensas y masivas protestas en puntos tan disímiles del territorio nacional como Cajamarca, Arequipa, Piura o la Amazonía. Se trata de diversas poblaciones que o

• Un ciclo diferente y mucho m s profundo de transformaciones

  2019-05-20

  

  Un ciclo diferente y mucho más profundo de transformaciones se inicia con el proceso constitucional en Bolivia y Ecuador. Bolivia se “re-funda” en 2009 y se proclama Estado Unitario Social de Derecho Plurinacional Comunitario. El capítulo cuarto sobre los derechos de las naciones y pueblos indígenas

• br Authorship br Conflict of interest

  2019-05-20

  

  Authorship Conflict of interest disclosure Introduction The Aurora kinases are serine/threonine protein kinases essential for regulation of normal D8-MMAE mitosis. Aurora kinases A (AAK) and B are overexpressed in hematologic malignancies, including acute myeloid leukemia (AML) and myelod

• The tumor microenvironment is enriched with

  2019-05-20

  

  The tumor microenvironment is enriched with EMVs that are derived not only by proliferating tumor cells, but also from infiltrating macrophages and neutrophils, and support tumor cell survival, growth, invasion and metastasis. Tumor derived EMVs also have the potential to modulate surrounding stroma

• July is a time to join together to make the

  2019-05-18

  

  July 28 is —a time to “join together to make the elimination of viral hepatitis our next greatest achievement”. Hepatitis is, belatedly, beginning to nudge its way into the global awareness. Having been neglected entirely in the Millennium Development Goals, it gets a name-check alongside AIDS, tube

• There were differentially expressed genes identified from th

  2019-05-18

  

  There were 3151 differentially expressed genes identified from the transcriptome profiling data of 497 patients (Fig. 2). Among these differentially expressed genes, 2190 genes were found to be upregulated in the group with infiltrating lymphocytes ≥1%. As shown in Table 2, these genes were enriched

• Pharmacokinetics analysis of AT on SCID mice bear http

  2019-05-18

  

  Pharmacokinetics analysis of AT-406 on SCID mice bearing MDA-MB-231 tumors has shown that AT-406 achieves a maximum concentration in plasma between 1.5μM and 9.9μM, and a maximum concentration in tumor tissue between 0.5μM and 18.2μM, depending on the dose and administration route (intravenous versu

• Preamble The J wave syndromes JWSs

  2019-05-18

  

  Preamble The J-wave syndromes (JWSs), consisting of the Brugada syndrome (BrS) and early repolarization syndrome (ERS), have captured the interest of the cardiology p-gp inhibitors over the past 2 decades following the identification of BrS as a new clinical entity by Pedro and Josep Brugada in 19

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