• Bisphosphonates significantly reduce or prevent SREs The use

  2019-06-25

  

  Bisphosphonates significantly reduce or prevent SREs. The use of Zol for patients with bone metastases is currently the gold standard treatment [4]. However, it is still unclear whether Zol contributes to a survival benefit [9]. Niikura et al. recently reported that Zol did not prolong progression-f

• Based on these preliminary clinical results with low dose in

  2019-06-25

  

  Based on these preliminary clinical results with low-dose, intermittent zoledronic acid, Hu et al. conducted a randomized phase II clinical study in order to clarify the role of metronomic low-dose zoledronic acid. Sixty breast cancer patients with bone metastases were randomized to receive either 1

• LQTS is classified into subtypes LQT

  2019-06-25

  

  LQTS is classified into subtypes LQT1 to LQT13 based on the site of genetic mutation. Each type possesses distinct clinical characteristics and a different prognosis. Treatment choice depends partly on individual phenotype and partly on genotype. Among Asian countries, several reports have been publ

• br es resultado de una larga investigaci n

  2019-06-25

  

  es resultado de una larga investigación de la obra de Juan Rulfo, pero es asimismo el fruto de largas reflexiones sobre “el arte de narrar” en general y sobre las relaciones que la literatura entabla con la cultura y la historia en que se inscribe, conexiones ellas mismas históricas. Desde el art

• En realidad el texto con el que Granada concluye

  2019-06-25

  

  En realidad el texto, con el que Granada concluye su Introducción al Símbolo de la Fé, consta de diez capítulos en los que se insiste en no explicar ampa receptors los que quieran convertirse de manera inmediata “los misterios del cristianismo, porque no creen aún, sino que hay que llevarlos por la

• Angler a registra la fauna en forma

  2019-06-25

  

  Anglería registra la Oxaliplatin structure en forma dispersa y fragmentaria; sucede casi siempre como una anécdota curiosa de marcado carácter digresivo o cuando el espécimen difiere ostensiblemente de los conocidos o es portador de alguna maravilla; además en su recepción y representación hay resa

• We established Wt and two Mt p R

  2019-06-25

  

  We established Wt- and two Mt- (p.R308P and p.A350_N351ins8)-GATA2-expressing 32D RJR-2403 oxalate weight to analyze the cellular effects of Mt-GATA2 (Fig. 3A). Immunofluorescence analysis revealed that Mt-GATA2 showed similar localization in the nucleus as Wt-GATA2 (Fig. 3B). Both Wt- and mutant-G

• Whole body CT only showed mild

  2019-06-25

  

  Whole-body CT only showed mild splenomegaly (14cm) and an enlarged iliac lymph node (1.5×3cm). Cranial MR yielded no specific findings. In the meantime, the patient was given Rituximab. He received 375mg/m2 of Rituximab per week, but after the third dose the patient rapidly developed shock and abdo

• Acetazolamide was unable to relieve the

  2019-06-25

  

  Acetazolamide was unable to relieve the headaches and was discontinued. Topiramate was initiated, with subsequent headache relief noted at a dose of 100mg orally twice daily. With this therapy, ATRA was able to be re-titrated to a maximum of 40mg orally twice daily (80% of initial dose) over two wee

• Although second malignancies are increasingly observed after

  2019-06-25

  

  Although second malignancies are increasingly observed after NHL, the incidence of CLL and RCC in the same patient is exceptional [4,5]. Nishikubo et al. [4] reported a case series of 8 patients with lymphoid malignancies and RCC. In 2 of 8 patients, CLL and T-cell CLL were diagnosed 1 year and 8 mo

• br VIII Si atendemos a

  2019-06-24

  

  VIII. Si atendemos Adapalene weight que Pablo del Prado en su Directorio espiritual, todavía en el año de 1650, incorporaba numerosas oraciones para la comunión espiritual indígena, junto a recomendaciones sobre la exclusión de la efectiva, no parece probable que se alcanzara nunca una normalizac

• En los bestiarios y cr nicas

  2019-06-24

  

  6. En los bestiarios y crónicas existe la intención de inducir el placer estético, acto que no es desinteresado, sino ligado a la contemplación de la divinidad, ya que la naturaleza es hermosa gracias a que la omnipotencia divina “resplandece” en ella: “el mundo sólo puede ser venustus, lindo, agrad

• While immunogenic action of langerhans cells had

  2019-06-24

  

  While immunogenic action of langerhans CMK had thoroughly been illustrated, their tolerogenic action is still being in its infancy stage. Ralph. M. Steinman shared the Nobel Prize in 2011 for his work on dendritic cells and their role in immunity. He uncovered the role of dendritic cells in periphe

• In our case the LV triggered

  2019-06-24

  

  In our case, the LV-triggered pace algorithm had 2 modes: “RVs” and “RVs+RVEs”. In the “RVs” mode, LV pacing synchronizes with RV-sensed events. It aims to maintain the CRT benefits even if intrinsic AV conduction shortens with an increase in sympathetic nerve activity. In the “RVs+RVEs” mode, LV pa

• br Case report A year old female presented with

  2019-06-24

  

  Case report A 50-year-old female presented with splenomegaly (24 cm) and pancytopenia in Mar. 2014. A bone marrow biopsy revealed hypocellular marrow (chloride channels of R-COP (Fig. 3). Further 5 cycles of cytotoxic therapy with standard dose R-CEOP (rituximab; cyclophosphamide; epirubicin; vi

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