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It has been reported that the FDP synthase in Hevea
2021-10-07

It has been reported that the FDP synthase in Hevea latex has a major role to produce the starter substrate FPP for the prenyl chain elongation in natural rubber biosynthesis (Takaya et al., 2003). Accumulation of HbFDP mRNA transcripts in different tissue types including latex (natural rubber) prod
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CMK br Conclusion H R H R and H R
2021-10-07

Conclusion H1R, H2R, and H3R mRNAs were expressed in rat OE. Moreover, these three histamine receptors were present in the cytoplasm of ORNs in OE. This is the first report of the expression and localization of histamine receptors in mammalian OE. These findings indicate that histamine may play a
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Histamine in the central nervous
2021-10-07

Histamine in the central nervous system is produced mainly in the tuberomammillary nucleus and is implicated in learning and memory as well as sleep and wakefulness, feeding and drinking, and neuroendocrine regulation . For instance, treatment with antihistamines not only produces drowsiness but als
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br Acknowledgements and disclosures This work was supported
2021-10-07

Acknowledgements and disclosures This work was supported in part by the National Institutes of Health (R01 HL-131673-01A1) and the Veterans Administration (BX-002539-01), United States. The authors have nothing to disclose concerning any conflict of interest. Introduction Adaptations are ofte
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br Other Functions of HCA Receptors HCA
2021-10-07

Other Functions of HCA Receptors HCA receptors, in particular HCA1, are expressed in various primary tumor elvitegravir 77, 78, 79. This is of interest, as most solid tumors show increased glucose uptake and lactate formation even under normoxic conditions, with lactate concentrations in the tum
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In our study we evaluated adenovirus type Ad as
2021-10-07

In our study we evaluated adenovirus type 5 (Ad5) as a vehicle for delivering Cre recombinase in conditional transgenic mouse based on the Cre-loxP system, in order to achieve GlyT1 gene modulation in a specific thalamic region in the adult animal. GlyT1 is a sodium- and chloride-coupled glycine tra
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Here we reported series of carbohydrate modified
2021-10-06

Here, we reported series of carbohydrate-modified compounds containing a dibromo substituted benzene ring which was derived from the red alga (). The conformation flexibility of equol receptor and their polyol structures give them many unique biological properties as we have described earlier. More
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Peripheral injury or disease induced alterations in synaptic
2021-10-06

Peripheral injury- or disease-induced alterations in synaptic efficacy occur not only at the first synapse made by the primary nociceptive afferents in the spinal dorsal horn but are also operational in several regions processing the sensorimotor as well as emotional-affective components of pain, su
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Nano biocatalyst prepared by assembling an enzyme on
2021-10-06

Nano-biocatalyst, prepared by assembling an enzyme on nanomaterial (NM) carriers is an emerging innovation in the field of nanobiotechnology. Some of the advantages of using NM as supports in Pam3CSK4 to conventional porous supports are effective enzyme loading due to large surface area with reduce
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br Ethics approval br Availability of
2021-10-04

Ethics approval Availability of data and materials Consent for publication Competing interests Authors contributions Introduction Glucose supply to tissues is maintained through a complex regulatory network mostly driven by the pancreatic hormones insulin and glucagon which control
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This connection is supported by studies in the
2021-10-03

This connection is supported by studies in the SIV macaque model of HIV, where treatment with methamphetamine, which greatly enhances CNS dopamine levels (Truong, 2005); increased 4-P-PDOT viral load. Methamphetamine also increased expression of the HIV co-receptor CCR5 in CNS macrophages, thereby
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Interestingly interactions between Smad and RhoA the other
2021-10-03

Interestingly, interactions between Smad3 and RhoA, the other small GTPase which is highly homologous to RhoB [9], could not be observed suggesting that the Smad3/RhoB interactions require amino l arabinose residues that are unique to RhoB. Combined with our previous observation that the RhoA gene,
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Indeed in women with different causes of epithelial layer da
2021-10-02

Indeed, in women with different causes of epithelial layer damage, HIV infection rates have been reported to be very high [2], [3]. As observed from in vivo studies, disruption of the epithelium due to pathogens [45], [46] or chemical irritants [47], has resulted in women being at a higher risk of H
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br Conclusions The whole mRNA
2021-10-02

Conclusions The whole mRNA sequence of equine HRG was identified. Consequently, we successfully generated recombinant equine HRG. By the Western blot procedure, blood HRG in horses was detected. Acknowledgments Introduction Alzheimer's disease (AD) is a chronic neurological disorder with c
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br Results and discussion br Conclusions TZDs
2021-10-02

Results and discussion Conclusions TZDs represent a well-studied group of antidiabetic agents. Based on previous observations of the ability of some TZDs to activate FFAR1, we designed five scaffolds consisting of the TZD head, a linker, and a carefully selected privileged structure. For the p
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